The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
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‘Certainly, which is about right. I seek for a physical knowledge of Organic units within a base-up way. I do think you may distinguish 3 strains of study in my group at the moment. The primary problems chromosome structure: How can you receive a metre-lengthy DNA polymer folded and organised in this type of microscopic cell? We have now developed visualisation strategies that let us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) in an effort to Make up chromosomes.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is always that these components jointly make up a residing system. The key of stated existence, I do think, lies inside the interactions, the interaction of These molecules. The large question with regard to the origin of existence remains unanswered. How did we ever evolve from basic molecules into your incredibly elaborate techniques we see currently? We have no idea. I would like to operate on These types of huge, open up questions.’
2011, first in vitro measurements of transportation throughout one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
What if, in place of making use of conventional prime-down silicon electronics, transistors might be crafted from the bottom up using solitary organic molecules as being the switching components? This concept, which turned The idea of now’s discipline of molecular electronics, to start with emerged while in the nineteen seventies.
It had been through this era that Dekker carried out study on magnetic spin techniques and on sound in superconductors and semiconductors.
Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
Several new phenomena have been discovered, and he and his exploration group founded a leading posture In this particular field of exploration. Dekker and his study team found new physics of nanotubes and explored the feasibility of molecular electronics. In 1998, they have been the main to create a transistor based on one nanotube molecule.
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It absolutely was an extremely appealing time, ceesdekker throughout which I acquired many support from Delft University of Know-how, where I was a professor at time, And that i begun several collaborations with molecular biologists. That assisted me understand lots.’